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ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — need advice Page 6

Got off metformin for the first time in 8 years - crying happy tears — need advice

gary_naperville Sun, Jun 15, 2025 at 9:24 PM 29 replies 1,622 viewsPage 6 of 6
anders_CPH
Senior Member
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Jun 16, 2025 at 5:54 AM#26

+1 to LipidDoc_ATL. Especially the point about "This is incredibly helpful..." — I have seen the same in my own experience with Got off metformin for the.

Last edited: Jun 16, 2025 at 9:54 AM
44 4CryptoCarl, MariaRD, AussieAnna and 41 others
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DanielChem_CHI
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Jun 16, 2025 at 6:11 AM#27

Bookmarked 📌 The Got off metformin info in this thread is essential. Coming back to this for sure.

44 6Dr.DermMIA, fiona_VT, denise_HTX and 41 others
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PharmacoVig_BOS
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Jun 16, 2025 at 6:28 AM#28

Clinical perspective on Got off metformin for the first time in:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Jun 16, 2025 at 9:28 AM
48 18DataDave, Dr.GutHealth, amsterdam_pete and 45 others
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CryptoCarl
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May 2024
Arizona
Jun 16, 2025 at 6:45 AM#29

Want to share my personal experience related to Got off metformin for the since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 278 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 38 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Got off metformin aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

10 13BethLabQueen, ChrisMacros, KetoKyle and 7 others
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GenomicsKate
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Oct 2024
Cambridge, MA
Jun 16, 2025 at 7:02 AM#30

Just wanted to say — for anyone reading this Got off metformin thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

Last edited: Jun 16, 2025 at 12:02 PM
12 0claudia_zurich, nancy_portland, rick_sfbay and 9 others
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