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ForumsPharmacology & MechanismsHas anyone dealt with molecular dynamics simulations of glp-1r binding? Page 7

Has anyone dealt with molecular dynamics simulations of glp-1r binding?

BrianDallas92 Sun, Jan 19, 2025 at 2:37 AM 36 replies 1,942 viewsPage 7 of 8
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Jan 19, 2025 at 12:32 PM#31

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Last edited: Jan 19, 2025 at 4:32 PM
3 6PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC
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pete_RVA
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Jan 19, 2025 at 12:49 PM#32

newstart_MO — that is really helpful context on Has anyone dealt with. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

37 10Dr.Martinez, mike_mod, SarahChen_PharmD and 34 others
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BrianDallas92
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Jan 19, 2025 at 1:06 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer BrianDallas92: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 19, 2025 at 2:06 PM
44 11andrew_nyc, Dr.EndoEP, GraceAZ_72 and 41 others
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tom_AK
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Jan 19, 2025 at 1:23 PM#34

pete_RVA — that is really helpful context on Has anyone dealt with. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Jan 19, 2025 at 5:23 PM
41 16jennifer_SEA, tyler_CSCS, VanRx_Mike and 38 others
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tammy_FL
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Jan 19, 2025 at 1:40 PM#35

Want to share my personal experience related to Has anyone dealt with since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 282 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 77 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

36 20mike_mealprep, NicoleRaleigh, james_edin and 33 others
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