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ForumsMetabolic Health & DiabetesGLP-1 and insulin resistance — my results so far Page 3

GLP-1 and insulin resistance — my results so far

sophie_paris Tue, May 13, 2025 at 12:19 AM 16 replies 1,582 viewsPage 3 of 4
JessicaM_2024
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Portland, OR
May 13, 2025 at 4:34 AM#11
BethLabQueen said:
GLP-1 and insulin resistance my is not that straightforward in my experience

This is exactly right. BethLabQueen articulated what I have been trying to explain to my doctor for months. The GLP-1 and insulin aspect is the most important factor.

8 6james_edin, FranDenver, Dr.BariatricHTX and 5 others
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jennifer_SEA
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Nov 2024
Seattle, WA
May 13, 2025 at 4:51 AM#12

Reading this thread on GLP-1 and insulin hits close to home. Night shift nurse — I started at 291 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 66 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1 and insulin — take the leap. It was the best health decision I have ever made. ❤️

25 23Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 22 others
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steph_laguna
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Nov 2024
Laguna Beach, CA
May 13, 2025 at 5:08 AM#13

sarah_TO — that is really helpful context on GLP-1 and insulin. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

24 24carl_compliance, DanielChem_CHI, marco_milano and 21 others
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LibrarianMeg
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Baltimore, MD
May 13, 2025 at 5:25 AM#14

To answer jennifer_SEA's question specifically:

From a clinical standpoint, GLP-1 and insulin resistance is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

30 1JessicaM_2024, TomFromTexas, mike.trainer_LA and 27 others
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carlos_SATX
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Oct 2024
San Antonio, TX
May 13, 2025 at 5:42 AM#15

Bookmarked 📌 The GLP-1 and insulin info in this thread is essential. Coming back to this for sure.

11 17tommy_boulder, hyun_seoul, jim_asheville and 8 others
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