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ForumsMetabolic Health & DiabetesSURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input Page 5

SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input

Admin Wed, Apr 16, 2025 at 7:09 AM 40 replies 1,896 viewsPage 5 of 8
tampaLisa73
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Tampa, FL
Apr 16, 2025 at 2:14 PM#21

Reading this thread on SURPASS-CVOT tirzepatide hits close to home. Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 52 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about SURPASS-CVOT — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Apr 16, 2025 at 3:14 PM
27 0RunnerRach, TrialNerd_Beth, HPLC_Greg and 24 others
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mike_mod
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Apr 16, 2025 at 2:31 PM#22

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Last edited: Apr 16, 2025 at 4:31 PM
50 12TomTeleRx, DoseLogDan, SleepFixSam and 47 others
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Dr.RaviCardio
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Apr 16, 2025 at 2:48 PM#23

Relevant to SURPASS-CVOT tirzepatide — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

45 20mark_tokyo, hans_munich, jason_sac26 and 42 others
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carl_compliance
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1,123
Nov 2024
Raleigh, NC
Apr 16, 2025 at 3:05 PM#24

Thank you kim_atl_prep! This is incredibly helpful. Taking this to my next appointment. 🙏

5 24FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 2 others
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wendy_avl
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Oct 2024
Asheville, NC
Apr 16, 2025 at 3:22 PM#25

+1 to Dr.RenalNash. Especially the point about "SURPASS-CVOT tirzepatide is exactly what..." — I have seen the same in my own experience with SURPASS-CVOT tirzepatide.

34 10RickReta_CO, PharmHunterJen, TomTeleRx and 31 others
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