🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild — anyone have experience? Page 4

So the drug literally changes your brain?? That is wild — anyone have experience?

Dr.PulmRoch Tue, Nov 5, 2024 at 1:55 PM 49 replies 2,218 viewsPage 4 of 10
Dr.PulmRoch
Member
456
2,345
Jun 2024
Rochester, MN
Nov 5, 2024 at 7:35 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on So the drug literally.

To answer sean_dublin: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

21 22rachel_ABQ, traveltech_sara, AttorneyGrant and 18 others
Reply Quote Save Share Report
dan_philly
Member
456
2,123
Jul 2024
Philadelphia, PA
Nov 5, 2024 at 7:52 PM#17

Adding my data to this So the drug literally discussion:

MetricBaselineMonth 3Month 8
Weight262 lbs237 lbs207 lbs
A1C6.6%5.8%5.4%
hsCRP6.02.01.2

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

5 3AmyNC_wife, SkepticalSean, Dr.CardioMD and 2 others
Reply Quote Save Share Report
adam_van
Member
212
890
Nov 2024
Vancouver, CA
Nov 5, 2024 at 8:09 PM#18

Agreed. My doctor said the same thing about So the drug.

14 7LindaRN_retired, tommy_boulder, hyun_seoul and 11 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Nov 5, 2024 at 8:26 PM#19

Slightly tangential to So the drug literally but Dr.SurgeonPGH reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

42 22Dr.PeteFamMed, claudia_zurich, nancy_portland and 39 others
Reply Quote Save Share Report
marcus_mpls
Member
234
1,123
Nov 2024
Minneapolis, MN
Nov 5, 2024 at 8:43 PM#20

+1 to Dr.PulmRoch. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with So the drug literally.

6 6mona_PHX, andrew_nyc, Dr.EndoEP and 3 others
Reply Quote Save Share Report

Similar Threads

GLP-1R desensitization — β-arrestin-mediated internalization18 replies
Biased agonism at GLP-1R — Gs vs β-arrestin signaling balance13 replies
Semaglutide albumin binding and the C-18 fatty acid linker17 replies
GIP receptor pharmacology — why GIP agonism enhances GLP-113 replies
Glucagon receptor signaling — hepatic glycogenolysis and lipolysis16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register