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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOrforglipron liver safety profile — hepatic considerations Page 4

Orforglipron liver safety profile — hepatic considerations

MASHdoc_SA Mon, Mar 2, 2026 at 5:37 PM 16 replies 520 viewsPage 4 of 4
NauseaFreeNow
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Mar 2, 2026 at 11:17 PM#16

Congrats LarryQC_SD!! You should be so proud of yourself. 🎉

19 14stefan_berlin, Dr.EM_Chicago, pete_RVA and 16 others
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Dr.NateNeph
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Mar 2, 2026 at 11:34 PM#17

+1. This mirrors my journey exactly. The Orforglipron liver discussion here is so valuable.

47 21NauseaFreeNow, SteveThurs, B12Beth and 44 others
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BenResearch_OR
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Mar 2, 2026 at 11:51 PM#18
mike_mod said:
Please remember to cite sources when making clinical claims

This is exactly right. mike_mod articulated what I have been trying to explain to my doctor for months. The Orforglipron liver safety aspect is the most important factor.

28 16Dr.NateNeph, PharmD_Rodriguez, julia.endo and 25 others
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Dr.BariatricHTX
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Mar 3, 2026 at 12:08 AM#19

Subscribing to this thread. Orforglipron liver safety is exactly what I've been researching. 🙏

15 18stefan_berlin, Dr.EM_Chicago, pete_RVA and 12 others
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Dr.EM_Chicago
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May 2024
Chicago, IL
Mar 3, 2026 at 12:25 AM#20

Slightly tangential to Orforglipron liver safety but fiona_VT reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 3, 2026 at 4:25 AM
12 0lisa_labSD, adam_van, Dr.SurgeonPGH and 9 others
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