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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — May 2025 Page 2

GLP-1 and gluconeogenesis — May 2025

sarah_nash92 Sun, Dec 29, 2024 at 6:16 PM 9 replies 1,616 viewsPage 2 of 2
VanRx_Mike
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Dec 29, 2024 at 9:06 PM#6

Congrats sarah_nash92!! Keep going — you're doing incredible. 🎉 👏

9 11Dr.LeslieOBGYN, MikeNYC_runner and 6 others
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Dr.NateNeph
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Dec 29, 2024 at 9:23 PM#7

Clinical perspective on GLP-1 and gluconeogenesis May 2025:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

27 20NauseaFreeNow, SteveThurs, B12Beth and 24 others
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PharmHunterJen
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Dec 29, 2024 at 9:40 PM#8

Subscribing to this thread. GLP-1 and gluconeogenesis is exactly what I've been researching. 🙏

2 24kevin_tulsa, Dr.PainCLE
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jason_paloalto
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Palo Alto, CA
Dec 29, 2024 at 9:57 PM#9

Reading this thread on GLP-1 and gluconeogenesis hits close to home. Dad of 2 checking in — I started at 289 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 64 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1 and gluconeoge — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 30, 2024 at 2:57 AM
26 23andrew_nyc, Dr.EndoEP, GraceAZ_72 and 23 others
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LarryQC_SD
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Jan 2024
San Diego, CA
Dec 29, 2024 at 10:14 PM#10
VanRx_Mike said:
Keep going — you're doing incredible

This is exactly right. VanRx_Mike articulated what I have been trying to explain to my doctor for months. The GLP-1 and gluconeogenesis aspect is the most important factor.

44 17dan_philly, MeganSA_TX, LarryQC_SD and 41 others
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