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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsReceptor internalization and recycling — my results so far Page 4

Receptor internalization and recycling — my results so far

SleepFixSam Thu, May 9, 2024 at 8:16 AM 18 replies 1,913 viewsPage 4 of 4
FitDadDave
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May 9, 2024 at 1:56 PM#16

Congrats marco_milano!! You should be so proud of yourself. 🎉

19 21Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 16 others
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ricardo_MIA
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Miami, FL
May 9, 2024 at 2:13 PM#17

SleepFixSam's experience with Receptor internalization resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I am on a different medication. But the overall trajectory has been remarkably similar. Down 67 lbs in 12 months.

One thing I would add that SleepFixSam did not mention: my sleep quality improved dramatically.

15 12ZaraB_AL, JakeSmashed95, NauseaFreeNow and 12 others
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Dr.SurgeonPGH
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May 9, 2024 at 2:30 PM#18

Bookmarked 📌 The Receptor internaliza info in this thread is essential. Coming back to this for sure.

27 12PharmHunterJen, TomTeleRx, DoseLogDan and 24 others
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Dr.EM_Chicago
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Chicago, IL
May 9, 2024 at 2:47 PM#19

Clinical perspective on Receptor internalization and recycling :

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: May 9, 2024 at 6:47 PM
49 7lucas_SP_BR, lisa_labSD, adam_van and 46 others
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marcus_mpls
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May 9, 2024 at 3:04 PM#20

Subscribing to this thread. Receptor internalization is exactly what I've been researching. 🙏

45 9mona_PHX, andrew_nyc, Dr.EndoEP and 42 others
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