🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — looking for input Page 4

Got off metformin for the first time in 8 years - crying happy tears — looking for input

ricardo_MIA Tue, Nov 5, 2024 at 9:41 PM 39 replies 1,834 viewsPage 4 of 8
ricardo_MIA
Member
378
1,678
Sep 2024
Miami, FL
Nov 6, 2024 at 3:21 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Got off metformin for the.

To answer BethLabQueen: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

44 16JakeSmashed95, NauseaFreeNow, SteveThurs and 41 others
Reply Quote Save Share Report
Dr.NateNeph
VIP Member
2,987
16,234
Dec 2023
Houston, TX
Nov 6, 2024 at 3:38 AM#17

Relevant to Got off metformin for the — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

33 17NauseaFreeNow, SteveThurs, B12Beth and 30 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Nov 6, 2024 at 3:55 AM#18

100%. My provider said the same thing about Got off metformin.

Last edited: Nov 6, 2024 at 5:55 AM
17 19DoseLogDan, SleepFixSam, PurityPaulOR and 14 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
BenResearch_OR
Senior Member
2,456
11,234
Dec 2023
Oregon
Nov 6, 2024 at 4:12 AM#19

Slightly tangential to Got off metformin for the but MikeNYC_runner reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

46 11Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 43 others
Reply Quote Save Share Report
PedsEndoPhilly
Member
345
1,890
Jun 2024
Philadelphia, PA
Nov 6, 2024 at 4:29 AM#20
ricardo_MIA said:
Thank you all for the thoughtful replies on Got off metformin for the

This is exactly right. ricardo_MIA articulated what I have been trying to explain to my doctor for months. The Got off metformin for the aspect is the most important factor.

Last edited: Nov 6, 2024 at 9:29 AM
28 17MikeNYC_runner and 25 others
Reply Quote Save Share Report

Similar Threads

SUSTAIN-6 to SELECT — the cardiovascular evidence timeline14 replies
GLP-1 and insulin resistance — HOMA-IR improvement data17 replies
Metabolic syndrome reversal criteria — how GLP-1 addresses all 55 replies
A1C target achievement rates — sema vs tirz comparison8 replies
SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register