🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsMolecular dynamics simulations of GLP-1R binding — anyone have experience? Page 7

Molecular dynamics simulations of GLP-1R binding — anyone have experience?

SkepticalSean Fri, Apr 26, 2024 at 8:00 AM 47 replies 3,019 viewsPage 7 of 10
wanda_boise
Member
412
1,890
Aug 2024
Boise, ID
Apr 26, 2024 at 5:55 PM#31

Following this thread closely. Molecular dynamics is something I'm actively working through.

41 1DanielChem_CHI, marco_milano, pam_columbus and 38 others
Reply Quote Save Share Report
FranDenver
Member
267
1,123
Oct 2024
Denver, CO
Apr 26, 2024 at 6:12 PM#32

Congrats SkepticalSean!! Keep going — you're doing incredible. 🎉

Last edited: Apr 27, 2024 at 12:12 AM
26 6LipidDoc_ATL, BariatricNurseD, MASHdoc_SA and 23 others
Reply Quote Save Share Report
SkepticalSean
Member
98
345
Jan 2025
Maine
Apr 26, 2024 at 6:29 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Molecular dynamics.

To answer SkepticalSean: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Apr 26, 2024 at 10:29 PM
46 6emma_london, tammy_FL, Dr.LipidDallas and 43 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
ingrid_STO
Member
345
1,456
Jul 2024
Stockholm, SE
Apr 26, 2024 at 6:46 PM#34
NauseaFreeNow said:
Night shift nurse — I started at 275 lbs and felt like I would tried everything

This is exactly right. NauseaFreeNow articulated what I have been trying to explain to my friends for months. The Molecular dynamics aspect is what made the difference for me.

Last edited: Apr 26, 2024 at 9:46 PM
3 1InsuranceTom, WendyG_ATL, SaraMom3
Reply Quote Save Share Report
JessicaH_TX
Senior Member
4,123
13,456
Dec 2023
Houston, TX
Apr 26, 2024 at 7:03 PM#35

Agreed. My doctor said the same thing about Molecular dynamics.

34 14tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 31 others
Reply Quote Save Share Report

Similar Threads

GLP-1R desensitization — β-arrestin-mediated internalization18 replies
Biased agonism at GLP-1R — Gs vs β-arrestin signaling balance13 replies
Semaglutide albumin binding and the C-18 fatty acid linker17 replies
GIP receptor pharmacology — why GIP agonism enhances GLP-113 replies
Glucagon receptor signaling — hepatic glycogenolysis and lipolysis16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register