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ForumsPharmacology & MechanismsHas anyone dealt with glp-1r allosteric modulators? Page 3

Has anyone dealt with glp-1r allosteric modulators?

Dr.RenalNash Sat, Apr 13, 2024 at 4:45 AM 23 replies 2,318 viewsPage 3 of 5
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Apr 13, 2024 at 9:00 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

40 13PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 37 others
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mike_nyc
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Apr 13, 2024 at 9:17 AM#12

Slightly tangential to Has anyone dealt with but TrialTracker_MD reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Apr 13, 2024 at 1:17 PM
41 7stefan_berlin, Dr.EM_Chicago, pete_RVA and 38 others
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rick_sfbay
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Apr 13, 2024 at 9:34 AM#13
mark_tokyo said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. mark_tokyo articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with aspect is the most important factor.

4 14james_edin, FranDenver, Dr.BariatricHTX and 1 other
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DanielChem_CHI
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Apr 13, 2024 at 9:51 AM#14

Saving this for reference. Top-tier content.

18 15ben_calgary, patPC_UT, Dr.DermMIA and 15 others
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dan_philly
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Apr 13, 2024 at 10:08 AM#15

Adding my data to this Has anyone dealt with discussion:

MetricBaselineMonth 4Month 8
Weight246 lbs246 lbs211 lbs
A1C7.0%6.2%5.4%
hsCRP5.03.01.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

47 10EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 44 others
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