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ForumsOral GLP-1 AgonistsDanuglipron BID dosing — 12 month update Page 4

Danuglipron BID dosing — 12 month update

nick_SD_fit Mon, Jan 19, 2026 at 6:49 PM 24 replies 747 viewsPage 4 of 5
WendyG_ATL
Member
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5,678
Apr 2024
Georgia
Jan 20, 2026 at 12:29 AM#16

Just wanted to say — for anyone reading this Danuglipron BID thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

Last edited: Jan 20, 2026 at 1:29 AM
6 15Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 3 others
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BiostatsBrad
Member
456
2,345
Jul 2024
Durham, NC
Jan 20, 2026 at 12:46 AM#17

Adding my data to this Danuglipron BID dosing discussion:

MetricBaselineMonth 4Month 8
Weight242 lbs247 lbs217 lbs
A1C6.6%6.2%5.4%
hsCRP6.03.00.8

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

Last edited: Jan 20, 2026 at 1:46 AM
6 8Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 3 others
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jason_sac26
New Member
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Jan 2026
Sacramento, CA
Jan 20, 2026 at 1:03 AM#18

Reading this thread on Danuglipron BID dosing hits close to home. Dad of 2 checking in — I started at 293 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 68 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Danuglipron BID — take the leap. It was the best health decision I have ever made. ❤️

2 6stefan_berlin, Dr.EM_Chicago
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FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Jan 20, 2026 at 1:20 AM#19

Adding my data to this Danuglipron BID dosing discussion:

MetricBaselineMonth 3Month 6
Weight264 lbs239 lbs219 lbs
A1C6.8%5.8%5.2%
hsCRP8.02.00.6

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

Last edited: Jan 20, 2026 at 4:20 AM
45 21Dr.LeslieOBGYN, MikeNYC_runner and 42 others
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MarkLI_maint
Member
534
2,345
Jun 2024
Long Island, NY
Jan 20, 2026 at 1:37 AM#20

Reading this thread on Danuglipron BID dosing hits close to home. Night shift nurse — I started at 275 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 50 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Danuglipron BID — take the leap. It was the best health decision I have ever made. ❤️

2 7bri_stats, pete_manc_UK
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