Reading this thread on GLP-1 and insulin hits close to home. Night shift nurse — I started at 291 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 66 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1 and insulin — take the leap. It was the best health decision I have ever made. ❤️

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Relevant to GLP-1 and insulin resistance — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Thank you tyler_CSCS! This is incredibly helpful. Bookmarking for later. 🙏

+1 to NurseLeah_Nash. Especially the point about "GLP-1 and insulin is exactly what I've b..." — I have seen the same in my own experience with GLP-1 and insulin.