Relevant to GLP-1 and insulin resistance — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 201 → 101 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Want to share my personal experience related to GLP-1 and insulin resistance since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 272 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 10 months later: I am down 82 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The GLP-1 and insulin aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
dave_SLC — that is really helpful context on GLP-1 and insulin. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsWant to share my personal experience related to GLP-1 and insulin resistance since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 289 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 16 months later: I am down 89 lbs, my labs have normalized, and I am off 2 of my 3 medications. The GLP-1 and insulin aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
dave_SLC — that is really helpful context on GLP-1 and insulin. Follow-up question: did you experience any side effects during this phase?
I am in a similar situation (about to start) and trying to set realistic expectations.