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ForumsPharmacology & MechanismsStructure-function of tirzepatide — 12 month update Page 9

Structure-function of tirzepatide — 12 month update

RunnerRach Mon, Mar 4, 2024 at 1:05 AM 50 replies 2,566 viewsPage 9 of 10
bri_stats
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May 2024
Seattle, WA
Mar 4, 2024 at 1:50 PM#41

Saving this for reference. Top-tier content.

Last edited: Mar 4, 2024 at 5:50 PM
41 23sarah_nash92, FitDadDave, RunnerRach and 38 others
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emily_PDX
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Nov 2024
Portland, OR
Mar 4, 2024 at 2:07 PM#42

Slightly tangential to Structure-function of but AmyNC_wife reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

4 23PharmD_Rodriguez, julia.endo, JessicaM_2024 and 1 other
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AttorneyGrant
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Mar 4, 2024 at 2:24 PM#43

Saving this for reference. Quality thread.

39 10JenMemphis, pat_auckland, Dr.GastroMayo and 36 others
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bbq_ray_KC
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Jul 2024
Kansas City, KS
Mar 4, 2024 at 2:41 PM#44

Want to share my personal experience related to Structure-function of since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 287 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 52 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Structure-function aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

24 13WendyG_ATL, SaraMom3, Dr.MetabolicMD and 21 others
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labquiet_amy
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Mar 2024
Cambridge, MA
Mar 4, 2024 at 2:58 PM#45

Relevant to Structure-function of — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 233 → 103 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

45 5pete_manc_UK, anna.melb_AU, mark_tokyo and 42 others
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