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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsWhy does it stop working after a while for some people — what worked for you? Page 2

Why does it stop working after a while for some people — what worked for you?

Dr.ObesityLA Mon, Feb 5, 2024 at 3:42 PM 19 replies 2,021 viewsPage 2 of 4
WendyG_ATL
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Georgia
Feb 5, 2024 at 6:32 PM#6

Congrats Dr.ObesityLA!! Keep going — you're doing incredible. 🎉

9 19Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 6 others
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hans_munich
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Munich, DE
Feb 5, 2024 at 6:49 PM#7

Clinical perspective on Why does it stop working after a while:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

10 14alex_tucson, kevin_tulsa, Dr.PainCLE and 7 others
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steve_okc
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Oklahoma City, OK
Feb 5, 2024 at 7:06 PM#8

Same experience here with Why does it stop working. Dr.ObesityLA described it perfectly.

37 16ZaraB_AL, JakeSmashed95, NauseaFreeNow and 34 others
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JenPlateau
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Nov 2024
Missouri
Feb 5, 2024 at 7:23 PM#9

Reading this thread on Why does it stop working hits close to home. Dad of 2 checking in — I started at 261 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 36 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Why does it stop — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Feb 6, 2024 at 1:23 AM
6 17FitDadDave, RunnerRach, TrialNerd_Beth and 3 others
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KarenAZ_mom
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Aug 2024
Scottsdale, AZ
Feb 5, 2024 at 7:40 PM#10
WendyG_ATL said:
Keep going — you're doing incredible

This is exactly right. WendyG_ATL articulated what I have been trying to explain to my doctor for months. The Why does it stop working aspect is the most important factor.

Last edited: Feb 6, 2024 at 12:40 AM
50 8HPLC_Greg, LibrarianMeg, bri_stats and 47 others
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