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ForumsMetabolic Health & DiabetesHas anyone dealt with surpass-cvot: tirzepatide cardiovascular outcomes trial design? Page 3

Has anyone dealt with surpass-cvot: tirzepatide cardiovascular outcomes trial design?

lori_vegas Sat, Aug 17, 2024 at 6:39 AM 11 replies 1,688 viewsPage 3 of 3
tom_AK
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Aug 17, 2024 at 10:54 AM#11

gary_naperville — wow. This community is amazing.

Last edited: Aug 17, 2024 at 2:54 PM
34 23steve_okc, dave_SLC, FDA_TrackerJim and 31 others
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MikeFit_NJ
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Apr 2024
New Jersey
Aug 17, 2024 at 11:11 AM#12

Slightly tangential to Has anyone dealt with but lori_vegas reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

40 21marcus_mpls, DeniseRN_TPA, SandraNC_45 and 37 others
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cory_ATX
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Jul 2024
Austin, TX
Aug 17, 2024 at 11:28 AM#13

Thanks for sharing this, lori_vegas. A few questions about your Has anyone dealt experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

38 1mona_PHX, andrew_nyc, Dr.EndoEP and 35 others
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lori_vegas
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Aug 2024
Las Vegas, NV
Aug 17, 2024 at 11:45 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer MikeFit_NJ: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

35 17tane_welly, Dr.PathRoch, mona_PHX and 32 others
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quinn_sf
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Jun 2024
San Francisco, CA
Aug 17, 2024 at 12:02 PM#15

Relevant to Has anyone dealt with — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 213 → 113 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Aug 17, 2024 at 6:02 PM
46 2Dr.EndoEP, GraceAZ_72, carl_compliance and 43 others
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