My endo and I disagree about so the drug literally changes your and I want a reality check.

They are saying that I do not need to worry about it but everything I have read here suggests otherwise.

I trust this community's collective knowledge but I also do not want to go against medical advice without good reason. What would you do?

LarryQC_SD's experience with So the drug literally resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 58 lbs in 13 months.

One thing I would add that LarryQC_SD did not mention: the mental health improvements were just as significant.

Thanks for sharing this, LarryQC_SD. A few questions about your So the drug experience:

1. What dose are you currently on?
2. How long before you noticed significant changes?
3. Did your doctor have any specific recommendations about So the drug?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on So the drug literally.

To answer InsuranceTom: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Relevant to So the drug literally changes — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 231 → 101 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.