Relevant to GLP-1 and beta-cell — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 219 → 119 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to GLP-1 and beta-cell since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 260 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 70 lbs, my labs have normalized, and I am off 2 of my 3 medications. The GLP-1 and beta-cell aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Relevant to GLP-1 and beta-cell — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 221 → 91 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to GLP-1 and beta-cell since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 277 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 77 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The GLP-1 and beta-cell aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

NicoleRaleigh — that is really helpful context on GLP-1 and beta-cell. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.