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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesGLP-1 and beta-cell preservation — looking for input Page 3

GLP-1 and beta-cell preservation — looking for input

steph_laguna Mon, Aug 5, 2024 at 6:17 AM 52 replies 2,916 viewsPage 3 of 11
gary_naperville
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Aug 5, 2024 at 10:32 AM#11
JennaRN said:
GLP-1 and beta-cell preservation is not that straightforward in my experience

This is exactly right. JennaRN articulated what I have been trying to explain to my doctor for months. The GLP-1 and beta-cell aspect is the most important factor.

Last edited: Aug 5, 2024 at 1:32 PM
11 12SleepFixSam, PurityPaulOR, MaxMetOK and 8 others
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LeilaHI
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Honolulu, HI
Aug 5, 2024 at 10:49 AM#12

Reading this thread on GLP-1 and beta-cell hits close to home. Night shift nurse — I started at 275 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 50 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1 and beta-cell — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Aug 5, 2024 at 3:49 PM
12 22VendorMark, COA_Karl, MikeFit_NJ and 9 others
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lucas_SP_BR
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São Paulo, BR
Aug 5, 2024 at 11:06 AM#13

Dr.PeteFamMed — that is really helpful context on GLP-1 and beta-cell. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

6 18zoe_NC, Dr.ObesityLA, NurseKim_ATL and 3 others
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Dr.RenalNash
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Aug 5, 2024 at 11:23 AM#14

To answer LeilaHI's question specifically:

From a clinical standpoint, GLP-1 and beta-cell is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

Last edited: Aug 5, 2024 at 4:23 PM
26 12anders_CPH, Dr.NutriCornell, pam_stl and 23 others
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TrialNerd_Beth
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Bethesda, MD
Aug 5, 2024 at 11:40 AM#15

Bookmarked 📌 The GLP-1 and beta-cell info in this thread is essential. Coming back to this for sure.

14 6SleepFixSam, PurityPaulOR, MaxMetOK and 11 others
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