Aug 5, 2024 at 1:22 PM#21
Congrats steph_laguna!! You should be so proud of yourself. 🎉
Last edited: Aug 5, 2024 at 2:22 PM
41 12JessicaM_2024, TomFromTexas, mike.trainer_LA and 38 others
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Aug 5, 2024 at 1:39 PM#22
Reading this thread on GLP-1 and beta-cell hits close to home. Dad of 2 checking in — I started at 265 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 40 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about GLP-1 and beta-cell — take the leap. It was the best health decision I have ever made. ❤️
24 15RunnerRach, TrialNerd_Beth, HPLC_Greg and 21 others
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Aug 5, 2024 at 1:56 PM#23
As a healthcare provider, I want to add some clinical context to this discussion on GLP-1 and beta-cell preservation .
Building on what AmyNC_wife said — the evidence base here is well-established. The key publications to reference are from the SURMOUNT program[1].
Key clinical points:
- Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
- Side effect profile is predictable and usually manageable with standard protocols
- Monitoring should include baseline labs and follow-up at 3-month intervals
- Patient education significantly improves outcomes and adherence
Standard disclaimer: this is educational, not individualized medical advice.
References:
[1] See thread title for relevant study identification.
[1] See thread title for relevant study identification.
45 1rachel_ABQ, traveltech_sara, AttorneyGrant and 42 others
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Sigma-Aldrich — Research-Grade Standards
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Shop Reference StandardsAug 5, 2024 at 2:13 PM#24
pete_manc_UK — wow. This community is amazing.
Last edited: Aug 5, 2024 at 8:13 PM
24 2Dr.PulmRoch, maya_sedona, stefan_berlin and 21 others
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Aug 5, 2024 at 2:30 PM#25
Adding my data to this GLP-1 and beta-cell discussion:
| Metric | Baseline | Month 5 | Month 8 |
|---|---|---|---|
| Weight | 258 lbs | 233 lbs | 203 lbs |
| A1C | 7.2% | 6.0% | 5.4% |
| hsCRP | 7.0 | 4.0 | 0.8 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.
1 2tampaLisa73
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