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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsHas anyone dealt with my pharmacist tried to explain the mechanism and my eyes glazed over? Page 5

Has anyone dealt with my pharmacist tried to explain the mechanism and my eyes glazed over?

labquiet_amy Mon, Dec 25, 2023 at 3:14 PM 34 replies 2,580 viewsPage 5 of 7
NauseaFreeNow
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Indiana
Dec 25, 2023 at 10:19 PM#21

sarah.morrison — that is really helpful context on Has anyone dealt with my. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

46 13stefan_berlin, Dr.EM_Chicago, pete_RVA and 43 others
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sophie_paris
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Paris, FR
Dec 25, 2023 at 10:36 PM#22

To answer FranDenver's question specifically:

From a clinical standpoint, Has anyone dealt with my is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Last edited: Dec 26, 2023 at 3:36 AM
7 16CryptoCarl, MariaRD, AussieAnna and 4 others
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JessicaH_TX
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Houston, TX
Dec 25, 2023 at 10:53 PM#23

Thank you NauseaFreeNow! This is incredibly helpful. Taking this to my next appointment. 🙏

6 6kim_atl_prep, sarah_TO, wendy_avl and 3 others
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hank_denver
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Sep 2024
Denver, CO
Dec 25, 2023 at 11:10 PM#24

Relevant to Has anyone dealt with my — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 191 → 91 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

7 3fiona_VT, denise_HTX, raj_cambridge and 4 others
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Dr.KarenChen
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San Francisco, CA
Dec 25, 2023 at 11:27 PM#25

Slightly tangential to Has anyone dealt with my but NauseaFreeNow reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

2 11sarah_nash92, FitDadDave
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