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ForumsPharmacology & MechanismsGLP-1R desensitization — looking for input Page 4

GLP-1R desensitization — looking for input

JakeBK_lifts Mon, Dec 11, 2023 at 9:07 AM 16 replies 2,188 viewsPage 4 of 4
denise_HTX
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Jan 2025
Houston, TX
Dec 11, 2023 at 2:47 PM#16

VanRx_Mike — wow. I've been looking for this exact info for weeks.

47 4sarah.morrison, NeuroNate, JessicaH_TX and 44 others
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labquiet_amy
Senior Member
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Mar 2024
Cambridge, MA
Dec 11, 2023 at 3:04 PM#17

Adding my data to this GLP-1R desensitization discussion:

MetricBaselineMonth 5Month 6
Weight240 lbs245 lbs215 lbs
A1C6.4%6.0%5.2%
hsCRP4.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

46 16HPLC_Greg, LibrarianMeg, bri_stats and 43 others
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SteveThurs
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Sep 2024
Wisconsin
Online
Dec 11, 2023 at 3:21 PM#18

Reading this thread on GLP-1R desensitization hits close to home. Night shift nurse — I started at 291 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 66 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1R desensitizati — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 11, 2023 at 7:21 PM
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TomFromTexas
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May 2024
Austin, TX
Dec 11, 2023 at 3:38 PM#19

denise_HTX — that is really helpful context on GLP-1R desensitization . Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

45 22PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 42 others
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NurseAsh_DET
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Sep 2024
Detroit, MI
Dec 11, 2023 at 3:55 PM#20

Reading this thread on GLP-1R desensitization hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1R desensitizati — take the leap. It was the best health decision I have ever made. ❤️

4 15emily_PDX, Dr.SleepRoch, laura_annarbor and 1 other
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