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ForumsPharmacology & MechanismsSemaglutide albumin binding and the C-18 fatty acid linker — 12 month update Page 3

Semaglutide albumin binding and the C-18 fatty acid linker — 12 month update

LindaRN_retired Sun, Nov 12, 2023 at 11:54 AM 31 replies 2,291 viewsPage 3 of 7
LeilaHI
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Nov 12, 2023 at 4:09 PM#11

+1 to LabKate. Especially the point about "Re: Semaglutide albumin binding — the ef..." — I have seen the same in my own experience with Semaglutide albumin.

1 20COA_Karl
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VendorMark
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Nov 12, 2023 at 4:26 PM#12

Want to share my personal experience related to Semaglutide albumin binding since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 246 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 76 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Semaglutide albumin aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

28 16KristenIndy, MarkLI_maint, Dr.PeteFamMed and 25 others
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SandraNC_45
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Nov 12, 2023 at 4:43 PM#13

jim_asheville — that is really helpful context on Semaglutide albumin. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

43 21NicoleRaleigh, james_edin, FranDenver and 40 others
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PharmacoVig_BOS
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Nov 12, 2023 at 5:00 PM#14

To answer VendorMark's question specifically:

From a clinical standpoint, Semaglutide albumin binding is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

18 4kate.chem, DataDave, Dr.GutHealth and 15 others
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BrianDallas92
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Nov 12, 2023 at 5:17 PM#15

Saving this for reference. Quality thread.

Last edited: Nov 12, 2023 at 6:17 PM
11 16GraceAZ_72, carl_compliance, DanielChem_CHI and 8 others
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