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ForumsMetabolic Health & DiabetesMetabolic syndrome reversal — need advice Page 5

Metabolic syndrome reversal — need advice

TirzTom Sat, Apr 13, 2024 at 12:31 PM 37 replies 2,432 viewsPage 5 of 8
MounjBrad
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Apr 13, 2024 at 7:36 PM#21

laura_annarbor — that is really helpful context on Metabolic syndrome. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Apr 14, 2024 at 12:36 AM
50 0patPC_UT, Dr.DermMIA, fiona_VT and 47 others
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Dr.ObesityMed
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Apr 13, 2024 at 7:53 PM#22

To answer InsuranceTom's question specifically:

From a clinical standpoint, Metabolic syndrome reversal is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

35 3PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 32 others
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pat_auckland
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Apr 13, 2024 at 8:10 PM#23

Thank you MounjBrad! This is incredibly helpful. Taking this to my next appointment. 🙏

30 2LarryQC_SD, wanda_boise, NurseAsh_DET and 27 others
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SleepDoc_PDX
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Apr 13, 2024 at 8:27 PM#24

Relevant to Metabolic syndrome reversal — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 239 → 109 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

40 2sophie_paris, mel_PDX, Dr.AddMedPHL and 37 others
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Dr.PathRoch
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Apr 13, 2024 at 8:44 PM#25

Slightly tangential to Metabolic syndrome but MounjBrad reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

30 24Dr.MetabolicMD, RetaRick_CA, JenPlateau and 27 others
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