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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral GLP-1 for elderly patients — September 2026 Page 2

Oral GLP-1 for elderly patients — September 2026

hans_munich Sun, Nov 2, 2025 at 7:29 AM 7 replies 906 viewsPage 2 of 2
mike.trainer_LA
Senior Member
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Los Angeles, CA
Nov 2, 2025 at 10:19 AM#6
Dr.NutriCornell said:
Short answer: talk to your prescriber first

Gonna push back on this one. Oral GLP-1 for elderly patients is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

Last edited: Nov 2, 2025 at 2:19 PM
49 3Dr.AddMedPHL, newstart_MO, mia_MS2 and 46 others
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SleepDoc_PDX
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Sep 2024
Portland, OR
Nov 2, 2025 at 10:36 AM#7

Adding my data to this Oral GLP-1 for elderly discussion:

MetricBaselineMonth 3Month 8
Weight250 lbs225 lbs195 lbs
A1C6.4%5.8%5.4%
hsCRP4.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

27 20hank_denver, carlos_SATX, sophie_paris and 24 others
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JakeSmashed95
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Arkansas
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Nov 2, 2025 at 10:53 AM#8

sean_dublin — wow. I've been looking for this exact info for weeks.

10 0alex_tucson, kevin_tulsa, Dr.PainCLE and 7 others
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jason_paloalto
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Nov 2024
Palo Alto, CA
Nov 2, 2025 at 11:10 AM#9

Slightly tangential to Oral GLP-1 for elderly but CryptoCarl reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

30 17andrew_nyc, Dr.EndoEP, GraceAZ_72 and 27 others
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mike_mod
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New York
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Nov 2, 2025 at 11:27 AM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

3 9PurityPaulOR, MaxMetOK, MounjBrad
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