Relevant to Wait so orforglipron means no — here is my latest bloodwork comparison:
Key improvements: A1C 8.0% → 5.3%, triglycerides 215 → 115 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Want to share my personal experience related to Wait so orforglipron means no since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 286 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 16 months later: I am down 41 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Wait so orforglipron aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
Dr.RaviCardio — that is really helpful context on Wait so orforglipron. Follow-up question: did you experience any side effects during this phase?
I am in a similar situation (about to start) and trying to set realistic expectations.
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View ResultsWant to share my personal experience related to Wait so orforglipron means no since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 258 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 8 months later: I am down 48 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Wait so orforglipron aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
newstart_MO — that is really helpful context on Wait so orforglipron. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.