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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsWait so orforglipron means no injection AND no fasting? Sign me up — anyone have experience? Page 7

Wait so orforglipron means no injection AND no fasting? Sign me up — anyone have experience?

VanRx_Mike Wed, Oct 15, 2025 at 1:19 PM 34 replies 1,190 viewsPage 7 of 7
marcus_mpls
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Minneapolis, MN
Oct 15, 2025 at 11:14 PM#31

Want to share my personal experience related to Wait so orforglipron means no since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 275 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 55 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Wait so orforglipron aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

41 15bbq_ray_KC, oliver_london, tane_welly and 38 others
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mike_nyc
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New York
Online
Oct 15, 2025 at 11:31 PM#32

Just wanted to say — for anyone reading this Wait so orforglipron thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

2 15stefan_berlin, Dr.EM_Chicago
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VanRx_Mike
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May 2024
Vancouver, CA
Oct 15, 2025 at 11:48 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Wait so orforglipron.

To answer VanRx_Mike: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

14 24Admin, Dr.Martinez, mike_mod and 11 others
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TrialNerd_Beth
Senior Member
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11,234
Jan 2024
Bethesda, MD
Oct 16, 2025 at 12:05 AM#34

Just wanted to say — for anyone reading this Wait so orforglipron thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

32 9DoseLogDan, SleepFixSam, PurityPaulOR and 29 others
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labquiet_amy
Senior Member
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Mar 2024
Cambridge, MA
Oct 16, 2025 at 12:22 AM#35

Yep. My endo said the same thing about Wait so orforglipron.

Last edited: Oct 16, 2025 at 2:22 AM
17 3pete_manc_UK, anna.melb_AU, mark_tokyo and 14 others
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