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ForumsOral GLP-1 AgonistsIs oral sema actually as effective as the injection version? — 12 month update Page 5

Is oral sema actually as effective as the injection version? — 12 month update

tommy_boulder Sat, Sep 20, 2025 at 3:17 AM 35 replies 1,548 viewsPage 5 of 7
KristenIndy
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May 2024
Indianapolis, IN
Sep 20, 2025 at 10:22 AM#21

Want to share my personal experience related to Is oral sema actually as since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 269 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 69 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Is oral sema aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Sep 20, 2025 at 3:22 PM
13 13LondonLisa, mike_nyc, VendorMark and 10 others
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mike_mod
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Sep 20, 2025 at 10:39 AM#22

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Sep 20, 2025 at 12:39 PM
4 23TomTeleRx, DoseLogDan, SleepFixSam and 1 other
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HPLC_Greg
Senior Member
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Feb 2024
Research Triangle, NC
Sep 20, 2025 at 10:56 AM#23

Adding my data to this Is oral sema actually as discussion:

MetricBaselineMonth 5Month 6
Weight276 lbs236 lbs221 lbs
A1C7.0%6.0%5.2%
hsCRP5.04.01.0

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

2 6RetaRick_CA, JenPlateau
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Dr.MetabolicMD
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Rochester, MN
Sep 20, 2025 at 11:13 AM#24

EndoResFellow — wow. This community is amazing.

Last edited: Sep 20, 2025 at 1:13 PM
38 17Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 35 others
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A1cHero_PHX
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Jul 2024
Phoenix, AZ
Sep 20, 2025 at 11:30 AM#25
Dr.SleepRoch said:
Is oral sema actually as is exactly what I've been researching

This is exactly right. Dr.SleepRoch articulated what I have been trying to explain to my friends for months. The Is oral sema actually as aspect is what made the difference for me.

Last edited: Sep 20, 2025 at 4:30 PM
7 23jason_sac26, chris_chi24, tampaLisa73 and 4 others
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