To answer newstart_MO's question specifically:

From a clinical standpoint, Metabolic syndrome reversal is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

Dr.NateNeph said:

5%, triglycerides 213 → 113 mg/dL, hsCRP 8

This is exactly right. Dr.NateNeph articulated what I have been trying to explain to my doctor for months. The Metabolic syndrome aspect is the most important factor.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Metabolic syndrome.

To answer anna.melb_AU: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

newstart_MO said:

Top-tier content

This is exactly right. newstart_MO articulated what I have been trying to explain to my friends for months. The Metabolic syndrome aspect is what made the difference for me.

This thread is incredible for Metabolic syndrome info. Better than most online groups.