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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMetabolic Health & DiabetesSURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — anyone have experience? Page 4

SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — anyone have experience?

MeganSA_TX Sat, Oct 14, 2023 at 10:31 AM 18 replies 2,325 viewsPage 4 of 4
MeganSA_TX
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Oct 14, 2023 at 4:11 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on SURPASS-CVOT tirzepatide.

To answer PharmacoVig_BOS: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

48 3PharmD_Rodriguez, julia.endo, JessicaM_2024 and 45 others
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FDA_TrackerJim
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Oct 14, 2023 at 4:28 PM#17

Adding my data to this SURPASS-CVOT tirzepatide discussion:

MetricBaselineMonth 4Month 8
Weight266 lbs236 lbs211 lbs
A1C7.0%6.2%5.4%
hsCRP5.03.00.8

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

42 4Admin, Dr.Martinez, mike_mod and 39 others
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Dr.MetabolicMD
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Oct 14, 2023 at 4:45 PM#18

Subscribing to this thread. SURPASS-CVOT tirzepatide is exactly what I've been researching. 🙏

Last edited: Oct 14, 2023 at 6:45 PM
39 8HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 36 others
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Dr.SurgeonPGH
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Oct 14, 2023 at 5:02 PM#19

Slightly tangential to SURPASS-CVOT tirzepatide but WendyG_ATL reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Oct 14, 2023 at 8:02 PM
46 1RickReta_CO, PharmHunterJen, TomTeleRx and 43 others
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hans_munich
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Oct 14, 2023 at 5:19 PM#20

+1 to MeganSA_TX. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with SURPASS-CVOT tirzepatide.

25 6emma_london, tammy_FL, Dr.LipidDallas and 22 others
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