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ForumsPsychological & BehavioralCompulsive shopping reduction on GLP-1 — reward pathway effects Page 4

Compulsive shopping reduction on GLP-1 — reward pathway effects

Dr.AddMedPHL Mon, Feb 16, 2026 at 10:47 AM 20 replies 793 viewsPage 4 of 4
denise_HTX
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Jan 2025
Houston, TX
Feb 16, 2026 at 4:27 PM#16

Just wanted to say — for anyone reading this Compulsive shopping thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

22 1sarah.morrison, NeuroNate, JessicaH_TX and 19 others
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andrew_nyc
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Apr 2024
New York, NY
Feb 16, 2026 at 4:44 PM#17

As a healthcare provider, I want to add some clinical context to this discussion on Compulsive shopping reduction on GLP-1 .

Building on what james_edin said — the evidence base here is well-established. The key publications to reference are from the STEP program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Feb 16, 2026 at 9:44 PM
17 14Dr.NateNeph, PharmD_Rodriguez, julia.endo and 14 others
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NurseKim_ATL
Senior Member
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Feb 2024
Atlanta, GA
Feb 16, 2026 at 5:01 PM#18
denise_HTX said:
The first few weeks are the hardest

Gonna push back on this one. Compulsive shopping reduction on is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

17 14ingrid_STO, pete_nash, hank_denver and 14 others
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BiostatsBrad
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Jul 2024
Durham, NC
Feb 16, 2026 at 5:18 PM#19

100%. My provider said the same thing about Compulsive shopping.

49 4james_edin, FranDenver, Dr.BariatricHTX and 46 others
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NurseAsh_DET
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Sep 2024
Detroit, MI
Feb 16, 2026 at 5:35 PM#20

Reading this thread on Compulsive shopping hits close to home. Dad of 2 checking in — I started at 293 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 68 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Compulsive shopping — take the leap. It was the best health decision I have ever made. ❤️

17 2emily_PDX, Dr.SleepRoch, laura_annarbor and 14 others
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