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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareWhat I wish I knew before starting GLP-1 therapy Page 2

What I wish I knew before starting GLP-1 therapy

sarah.morrison Wed, Mar 11, 2026 at 9:24 PM 14 replies 363 viewsPage 2 of 3
TinaHashiRN
Member
345
1,567
Sep 2024
Raleigh, NC
Mar 12, 2026 at 12:14 AM#6

WATER WATER WATER. I cannot stress this enough. I ended up in urgent care with dehydration month 2 because I "wasn't thirsty." Your thirst signals get weird on this stuff. Track your water intake. 64oz MINIMUM.

38 15SarahChen_PharmD, sarah.morrison, NeuroNate and 35 others
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DanielChem_CHI
Senior Member
1,234
5,678
Mar 2024
Chicago, IL
Mar 12, 2026 at 12:31 AM#7

Also: take progress photos even if you hate them. I didn't take any for the first 3 months and I genuinely regret it. The mirror lies. Photos don't.

Last edited: Mar 12, 2026 at 2:31 AM
38 22Dr.DermMIA, fiona_VT, denise_HTX and 35 others
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jason_sac26
New Member
34
123
Jan 2026
Sacramento, CA
Mar 12, 2026 at 12:48 AM#8

Emotional one: some days you'll grieve food. Like actually grieve it. The relationship you had with food was complicated and changing it is a form of loss. That's normal and it's ok to feel sad about it. Get a therapist if you can.

41 15stefan_berlin, Dr.EM_Chicago, pete_RVA and 38 others
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tampaLisa73
Member
312
1,456
Oct 2024
Tampa, FL
Mar 12, 2026 at 1:05 AM#9

Gina 🥺 yes. This one. I wasn't ready for how emotional it would be to not find comfort in food anymore. I had to find new coping mechanisms and it was genuinely hard. But worth it.

Last edited: Mar 12, 2026 at 2:05 AM
39 15mike.trainer_LA, sarah_nash92, FitDadDave and 36 others
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MaxMetOK
Member
312
1,123
Dec 2024
Oklahoma
Mar 12, 2026 at 1:22 AM#10

One more: TELL YOUR DENTIST. Seriously. The reduced eating + possible acid reflux can affect your teeth. My dentist was like "what changed" and when I told her she had a whole protocol for it. They need to know.

34 23PurityPaulOR, MaxMetOK, MounjBrad and 31 others
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