May 21, 2025 at 9:52 PM#26
Same experience here with ATTAIN-2 orforglipron in. tommy_boulder described it perfectly.
36 22anna.melb_AU, mark_tokyo, hans_munich and 33 others
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May 21, 2025 at 10:09 PM#27
fiona_glasgow said:I started my GLP-1 journey in March 2025 at 271 lbs with metabolic syndrome
Gonna push back on this one. ATTAIN-2 orforglipron in T2DM 12 is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.
Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.
Last edited: May 21, 2025 at 11:09 PM
30 17PharmD_Rodriguez, julia.endo, JessicaM_2024 and 27 others
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May 21, 2025 at 10:26 PM#28
Want to share my personal experience related to ATTAIN-2 orforglipron in T2DM since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 277 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 14 months later: I am down 72 lbs, my labs have normalized, and I am off 2 of my 3 medications. The ATTAIN-2 orforglipro aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
3 15NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin
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Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsMay 21, 2025 at 10:43 PM#29
Saving this for reference. Top-tier content.
45 10lori_vegas, Dr.PulmRoch, maya_sedona and 42 others
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May 21, 2025 at 11:00 PM#30
julia.endo — that is really helpful context on ATTAIN-2 orforglipron in. Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.
Last edited: May 22, 2025 at 1:00 AM
18 12SallyK_inj, CryptoCarl, MariaRD and 15 others
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