Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.
Thread quality is excellent — keep it up. 👍
Clinical perspective on Anyone else feel guilty for using a drug:
I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.
For this specific question, I would recommend: reviewing the relevant clinical guidelines.
Admin said:Just a reminder to keep things civil and evidence-based
I respect Admin perspective but I think this oversimplifies things a bit. Re: Anyone else feel guilty for — the effect size varies considerably by population.
I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.
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