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ForumsOral GLP-1 AgonistsOral GLP-1 for elderly patients — anyone have experience? Page 2

Oral GLP-1 for elderly patients — anyone have experience?

EndoResFellow Wed, Apr 16, 2025 at 4:27 AM 45 replies 2,071 viewsPage 2 of 9
nick_SD_fit
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Sep 2024
San Diego, CA
Apr 16, 2025 at 7:17 AM#6

Just wanted to say — for anyone reading this Oral GLP-1 for thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

2 5SkepticalSean, Dr.CardioMD
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ingrid_STO
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Jul 2024
Stockholm, SE
Apr 16, 2025 at 7:34 AM#7

As a pharmacist, I want to add some clinical context to this discussion on Oral GLP-1 for elderly patients anyone.

Building on what EndoResFellow said — the evidence base here is robust. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Apr 16, 2025 at 10:34 AM
5 21COA_Karl, MikeFit_NJ, InsuranceTom and 2 others
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tyler_CSCS
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Jun 2024
Phoenix, AZ
Apr 16, 2025 at 7:51 AM#8

Subscribing to this thread. Oral GLP-1 for elderly is exactly what I've been researching. 🙏

7 14Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC and 4 others
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nick_newbie
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Virginia
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Apr 16, 2025 at 8:08 AM#9

Want to share my personal experience related to Oral GLP-1 for elderly since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 266 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 61 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Oral GLP-1 for aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

34 9LarryQC_SD, wanda_boise, NurseAsh_DET and 31 others
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mike_mealprep
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Jul 2024
Chicago, IL
Apr 16, 2025 at 8:25 AM#10

+1 to nick_SD_fit. Especially the point about "The first month are the hardest..." — I have seen the same in my own experience with Oral GLP-1 for elderly.

31 18sophie_paris, mel_PDX, Dr.AddMedPHL and 28 others
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