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ForumsOral GLP-1 AgonistsOral GLP-1 for elderly patients — anyone have experience? Page 3

Oral GLP-1 for elderly patients — anyone have experience?

EndoResFellow Wed, Apr 16, 2025 at 4:27 AM 45 replies 2,071 viewsPage 3 of 9
sarah_nash92
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Jun 2024
Nashville, TN
Apr 16, 2025 at 8:42 AM#11

Thank you tyler_CSCS! This is incredibly helpful. Taking this to my next appointment. 🙏

20 12NauseaFreeNow, SteveThurs, B12Beth and 17 others
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denise_HTX
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145
678
Jan 2025
Houston, TX
Apr 16, 2025 at 8:59 AM#12

Slightly tangential to Oral GLP-1 for elderly but EndoResFellow reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

23 4NeuroNate, JessicaH_TX, KevinCompounds and 20 others
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stefan_berlin
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234
1,123
Oct 2024
Berlin, DE
Apr 16, 2025 at 9:16 AM#13

Thanks for sharing this, EndoResFellow. A few questions about your Oral GLP-1 for experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Oral GLP-1 for?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

21 15KevinCompounds, TirzTom, TrialTracker_MD and 18 others
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EndoResFellow
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2,345
Sep 2024
Baltimore, MD
Apr 16, 2025 at 9:33 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Oral GLP-1 for elderly.

To answer denise_HTX: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

21 17NurseKim_ATL, paul_denver, TinaHashiRN and 18 others
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BiostatsBrad
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Jul 2024
Durham, NC
Apr 16, 2025 at 9:50 AM#15

Adding my data to this Oral GLP-1 for elderly discussion:

MetricBaselineMonth 3Month 8
Weight242 lbs237 lbs207 lbs
A1C6.6%5.8%5.4%
hsCRP6.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

9 24NicoleRaleigh, james_edin, FranDenver and 6 others
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