Dr.NateNeph — that is really helpful context on Has anyone dealt with. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
To answer carlos_SATX's question specifically:
From a clinical standpoint, Has anyone dealt with is a reasonable concern that deserves a thorough answer.
The short answer: the evidence supports this approach for most patients.
The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.
Thank you SleepDoc_PDX! This is incredibly helpful. Taking this to my next appointment. 🙏
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Shop Reference StandardsRelevant to Has anyone dealt with — here is my latest bloodwork comparison:
Key improvements: A1C 8.0% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Slightly tangential to Has anyone dealt with but SleepDoc_PDX reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.