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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralGLP-1 and addiction pathways — looking for input Page 3

GLP-1 and addiction pathways — looking for input

DanielChem_CHI Thu, Jan 8, 2026 at 12:31 PM 12 replies 857 viewsPage 3 of 3
Dr.NephBHM_UK
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Jan 8, 2026 at 4:46 PM#11

nick_newbie — wow. I've been looking for this exact info for weeks.

1 22Dr.CardioMD
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maria_elpaso
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Sep 2024
El Paso, TX
Jan 8, 2026 at 5:03 PM#12

Slightly tangential to GLP-1 and addiction but DanielChem_CHI reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

48 5RunnerRach, TrialNerd_Beth, HPLC_Greg and 45 others
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tommy_boulder
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Nov 2024
Boulder, CO
Jan 8, 2026 at 5:20 PM#13

Thanks for sharing this, DanielChem_CHI. A few questions about your GLP-1 and addiction experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about GLP-1 and addic?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

19 11robert_kc, dan_philly, MeganSA_TX and 16 others
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DanielChem_CHI
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Mar 2024
Chicago, IL
Jan 8, 2026 at 5:37 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and addiction.

To answer maria_elpaso: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 8, 2026 at 7:37 PM
34 2ben_calgary, patPC_UT, Dr.DermMIA and 31 others
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josh_phd_bmore
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Jul 2024
Baltimore, MD
Jan 8, 2026 at 5:54 PM#15

Relevant to GLP-1 and addiction pathways — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

50 13tampaLisa73, KarenAZ_mom, zoe_NC and 47 others
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