TrialTracker_MD said:

— in my experience this comes down to a few key factors

I respect TrialTracker_MD perspective but I think this oversimplifies things a bit. Re: Compounded sema shortage — the effect size varies considerably by population.

I am not saying TrialTracker_MD wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Relevant to Compounded sema shortage — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 231 → 101 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Thank you Dr.LeslieOBGYN! This is incredibly helpful. Bookmarking for later. 🙏

Slightly tangential to Compounded sema shortage but tony_orlando reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍