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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsHow far away are we really from an oral option — 12 month update Page 7

How far away are we really from an oral option — 12 month update

HPLC_Greg Sun, Mar 9, 2025 at 7:45 PM 47 replies 2,552 viewsPage 7 of 10
JessicaM_2024
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Mar 2024
Portland, OR
Mar 10, 2025 at 5:40 AM#31

Same experience here with How far away are we. TomTeleRx described it perfectly.

Last edited: Mar 10, 2025 at 6:40 AM
11 10james_edin, FranDenver, Dr.BariatricHTX and 8 others
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jennifer_SEA
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Nov 2024
Seattle, WA
Mar 10, 2025 at 5:57 AM#32

Slightly tangential to How far away are we but TrialTracker_MD reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

21 12Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 18 others
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HPLC_Greg
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Research Triangle, NC
Mar 10, 2025 at 6:14 AM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on How far away are we.

To answer HPLC_Greg: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

33 3RetaRick_CA, JenPlateau, SallyK_inj and 30 others
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Dr.RheumBOS
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Apr 2024
Boston, MA
Mar 10, 2025 at 6:31 AM#34

Reading this thread on How far away are we hits close to home. Night shift nurse — I started at 263 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 38 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about How far away are we — take the leap. It was the best health decision I have ever made. ❤️

33 18lori_vegas, Dr.PulmRoch, maya_sedona and 30 others
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VendorMark
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Texas
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Mar 10, 2025 at 6:48 AM#35

Adding my data to this How far away are we discussion:

MetricBaselineMonth 4Month 8
Weight274 lbs224 lbs199 lbs
A1C6.8%6.2%5.4%
hsCRP8.03.00.8

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

23 15claudia_zurich, nancy_portland, rick_sfbay and 20 others
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