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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsDropped my Rybelsus in the toilet this morning - worst day — what worked for you? Page 3

Dropped my Rybelsus in the toilet this morning - worst day — what worked for you?

paul_denver Tue, Feb 18, 2025 at 9:29 AM 18 replies 1,694 viewsPage 3 of 4
marcus_mpls
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Minneapolis, MN
Feb 18, 2025 at 1:44 PM#11

DeniseRN_TPA — wow. This community is amazing.

39 7bbq_ray_KC, oliver_london, tane_welly and 36 others
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PedsEndoPhilly
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Philadelphia, PA
Feb 18, 2025 at 2:01 PM#12

Slightly tangential to Dropped my Rybelsus in but paul_denver reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

1 12wendy_avl
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zoe_NC
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Nov 2024
Charlotte, NC
Feb 18, 2025 at 2:18 PM#13

Thanks for sharing this, paul_denver. A few questions about your Dropped my Rybelsus experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Dropped my Rybe?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

27 23james_edin, FranDenver, Dr.BariatricHTX and 24 others
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paul_denver
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May 2024
Denver, CO
Feb 18, 2025 at 2:35 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Dropped my Rybelsus in.

To answer PedsEndoPhilly: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

25 17sarah_TO, wendy_avl, jason_paloalto and 22 others
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labquiet_amy
Senior Member
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Mar 2024
Cambridge, MA
Feb 18, 2025 at 2:52 PM#15

Relevant to Dropped my Rybelsus in the — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

25 13pete_manc_UK, anna.melb_AU, mark_tokyo and 22 others
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