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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralGrief over lost years — what worked for you? Page 2

Grief over lost years — what worked for you?

Dr.NephBHM_UK Mon, Dec 22, 2025 at 1:32 PM 9 replies 735 viewsPage 2 of 2
mike_nyc
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Dec 22, 2025 at 4:22 PM#6
BariatricNurseD said:
— in my experience this comes down to a few key factors

Gonna push back on this one. Grief over lost years what worked is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

48 14maya_sedona, stefan_berlin, Dr.EM_Chicago and 45 others
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Dr.AddMedPHL
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Dec 22, 2025 at 4:39 PM#7

Adding my data to this Grief over lost years discussion:

MetricBaselineMonth 5Month 8
Weight262 lbs242 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

7 16sarah_nash92, FitDadDave, RunnerRach and 4 others
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Dr.LeslieOBGYN
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Dec 22, 2025 at 4:56 PM#8

Dr.GastroMayo — wow. I've been looking for this exact info for weeks.

Last edited: Dec 22, 2025 at 10:56 PM
22 15james_edin, FranDenver, Dr.BariatricHTX and 19 others
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andrew_nyc
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Dec 22, 2025 at 5:13 PM#9

Slightly tangential to Grief over lost years but mike_mealprep reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

28 3julia.endo, JessicaM_2024, TomFromTexas and 25 others
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mike_mod
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Dec 22, 2025 at 5:30 PM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

12 19PurityPaulOR, MaxMetOK, MounjBrad and 9 others
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