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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsIs oral sema actually as effective as the injection version? — my results so far Page 3

Is oral sema actually as effective as the injection version? — my results so far

NurseAsh_DET Sat, Feb 8, 2025 at 11:52 AM 14 replies 1,585 viewsPage 3 of 3
adam_van
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Nov 2024
Vancouver, CA
Feb 8, 2025 at 4:07 PM#11

mel_PDX — wow. I've been looking for this exact info for weeks.

18 15FranDenver, Dr.BariatricHTX, LindaRN_retired and 15 others
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DadBodDave
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Nov 2024
Ohio
Feb 8, 2025 at 4:24 PM#12

Slightly tangential to Is oral sema actually as but NurseAsh_DET reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

48 2JenMemphis, pat_auckland, Dr.GastroMayo and 45 others
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kim_atl_prep
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Aug 2024
Atlanta, GA
Feb 8, 2025 at 4:41 PM#13

Thanks for sharing this, NurseAsh_DET. A few questions about your Is oral sema experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Is oral sema?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Feb 8, 2025 at 10:41 PM
36 0RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 33 others
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NurseAsh_DET
Member
356
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Sep 2024
Detroit, MI
Feb 8, 2025 at 4:58 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Is oral sema actually as.

To answer DadBodDave: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

3 15labquiet_amy, emily_PDX, Dr.SleepRoch
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LabKate
Senior Member
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Jan 2024
Oregon
Feb 8, 2025 at 5:15 PM#15

Relevant to Is oral sema actually as — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 231 → 101 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

4 2labquiet_amy, emily_PDX, Dr.SleepRoch and 1 other
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