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ForumsPublic SquareThe "Ozempic face" phenomenon — adipose redistribution or volume loss? Page 3

The "Ozempic face" phenomenon — adipose redistribution or volume loss?

Dr.Martinez Sun, Feb 8, 2026 at 9:00 AM 14 replies 747 viewsPage 3 of 3
Admin
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Feb 8, 2026 at 1:15 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Feb 8, 2026 at 5:15 PM
6 1PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 3 others
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Dr.MetabolicMD
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Feb 8, 2026 at 1:32 PM#12

Clinical perspective on The "Ozempic face" phenomenon adipose:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

14 19PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 11 others
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labquiet_amy
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Feb 8, 2026 at 1:49 PM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: The "Ozempic face" phenomenon — the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

9 9LibrarianMeg, bri_stats, pete_manc_UK and 6 others
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jennifer_SEA
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Feb 8, 2026 at 2:06 PM#14

Reading this thread on The "Ozempic face" hits close to home. Night shift nurse — I started at 267 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 42 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about The "Ozempic face" — take the leap. It was the best health decision I have ever made. ❤️

23 22jim_asheville, matt_MKE, Dr.ReproEndo and 20 others
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matt_MKE
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Feb 8, 2026 at 2:23 PM#15

Bookmarked 📌 The The "Ozempic face" info in this thread is essential. Coming back to this for sure.

9 9DanielChem_CHI, marco_milano, pam_columbus and 6 others
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