🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral vs injectable GLP-1: bioavailability and efficacy comparison — need advice Page 3

Oral vs injectable GLP-1: bioavailability and efficacy comparison — need advice

mike_mealprep Sun, Dec 29, 2024 at 3:34 PM 12 replies 1,712 viewsPage 3 of 3
pete_RVA
Member
178
890
Dec 2024
Richmond, VA
Dec 29, 2024 at 7:49 PM#11

MounjBrad — wow. I've been looking for this exact info for weeks.

1 17mike_mod
Reply Quote Save Share Report
KarenAZ_mom
Member
567
2,567
Aug 2024
Scottsdale, AZ
Dec 29, 2024 at 8:06 PM#12

Slightly tangential to Oral vs injectable GLP-1 but mike_mealprep reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

8 4pete_manc_UK, anna.melb_AU, mark_tokyo and 5 others
Reply Quote Save Share Report
JakeSmashed95
Member
412
1,890
Aug 2024
Arkansas
Online
Dec 29, 2024 at 8:23 PM#13

Thanks for sharing this, mike_mealprep. A few questions about your Oral vs injectable experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Oral vs injecta?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

7 22alex_tucson, kevin_tulsa, Dr.PainCLE and 4 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
mike_mealprep
Member
412
1,890
Jul 2024
Chicago, IL
Dec 29, 2024 at 8:40 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Oral vs injectable GLP-1.

To answer KarenAZ_mom: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Dec 30, 2024 at 2:40 AM
27 11mel_PDX, Dr.AddMedPHL, newstart_MO and 24 others
Reply Quote Save Share Report
labquiet_amy
Senior Member
1,234
6,789
Mar 2024
Cambridge, MA
Dec 29, 2024 at 8:57 PM#15

Relevant to Oral vs injectable GLP-1 — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

1 2pete_manc_UK
Reply Quote Save Share Report

Similar Threads

Orforglipron Phase 3 ATTAIN-1 topline — oral non-peptide GLP-116 replies
Oral semaglutide 50mg (Rybelsus HD) — OASIS program results12 replies
Danuglipron BID dosing — Pfizer oral GLP-1 update7 replies
Oral vs injectable GLP-1: bioavailability and efficacy comparison5 replies
Orforglipron food interaction profile — no fasting requirement15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register