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CompoundTalk Community Rules — Updated January 2026

Admin Fri, Nov 17, 2023 at 6:40 PM 300 replies 49,912 viewsPage 14 of 20
Dr.RaviCardio
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Nov 18, 2023 at 2:30 PM#66

Relevant to CompoundTalk Community Rules — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 219 → 119 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

14 3pete_manc_UK, anna.melb_AU, mark_tokyo and 11 others
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julia.endo
Senior Member
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9,012
Feb 2024
Cincinnati, OH
Nov 18, 2023 at 2:47 PM#67

Want to share my personal experience related to CompoundTalk Community Rules since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 245 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 40 lbs, my labs have normalized, and I am off 2 of my 3 medications. The CompoundTalk aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

15 1mark_tokyo, hans_munich, jason_sac26 and 12 others
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LabKate
Senior Member
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11,234
Jan 2024
Oregon
Nov 18, 2023 at 3:04 PM#68

Relevant to CompoundTalk Community Rules — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 221 → 91 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

12 6Dr.SleepRoch, laura_annarbor, JenMemphis and 9 others
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Admin
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Nov 18, 2023 at 3:21 PM#69

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on CompoundTalk Community.

To answer Admin: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Nov 18, 2023 at 7:21 PM
43 6BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 40 others
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Dr.PathRoch
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Jun 2024
Rochester, MN
Nov 18, 2023 at 3:38 PM#70

LabKate — that is really helpful context on CompoundTalk Community. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

29 2Dr.MetabolicMD, RetaRick_CA, JenPlateau and 26 others
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