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ForumsOral GLP-1 AgonistsOrforglipron and hepatic first-pass metabolism — anyone have experience? Page 8

Orforglipron and hepatic first-pass metabolism — anyone have experience?

Dr.EM_Chicago Tue, Nov 5, 2024 at 6:59 PM 44 replies 1,967 viewsPage 8 of 9
MeganSA_TX
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Nov 6, 2024 at 6:19 AM#36

Slightly tangential to Orforglipron and hepatic but TomTeleRx reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Nov 6, 2024 at 8:19 AM
10 21PharmD_Rodriguez, julia.endo, JessicaM_2024 and 7 others
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mike_mealprep
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Nov 6, 2024 at 6:36 AM#37

Subscribing to this thread. Orforglipron and hepatic is exactly what I've been researching. 🙏

Last edited: Nov 6, 2024 at 12:36 PM
48 24newstart_MO, mia_MS2, LeilaHI and 45 others
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lori_vegas
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Nov 6, 2024 at 6:53 AM#38

Slightly tangential to Orforglipron and hepatic but RegAffairsDC reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

17 1oliver_london, tane_welly, Dr.PathRoch and 14 others
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fiona_VT
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Vermont
Nov 6, 2024 at 7:10 AM#39

Agreed. My doctor said the same thing about Orforglipron and.

1 20chris_chi24
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SarahChen_PharmD
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Nov 6, 2024 at 7:27 AM#40

Slightly tangential to Orforglipron and hepatic but RegAffairsDC reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

24 16robert_kc, dan_philly, MeganSA_TX and 21 others
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