Nov 6, 2024 at 7:44 AM#41
Saving this for reference. Top-tier content.
40 10Dr.PainCLE, mike_mealprep, NicoleRaleigh and 37 others
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Nov 6, 2024 at 8:01 AM#42
Slightly tangential to Orforglipron and hepatic but SarahChen_PharmD reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
32 8NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 29 others
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Nov 6, 2024 at 8:18 AM#43
Saving this for reference. Quality thread.
50 18pam_columbus, nick_SD_fit, ben_calgary and 47 others
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Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsNov 6, 2024 at 8:35 AM#44
Want to share my personal experience related to Orforglipron and hepatic since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 287 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 10 months later: I am down 47 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Orforglipron and aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
Last edited: Nov 6, 2024 at 2:35 PM
25 15MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 22 others
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Nov 6, 2024 at 8:52 AM#45
Relevant to Orforglipron and hepatic — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 233 → 103 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
9 3NicoleRaleigh, james_edin, FranDenver and 6 others
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