GLP-1 therapy in patients over 65 — safety and efficacy data

Saw this come across my feed today and thought the community would want to discuss.

GLP-1 therapy in patients over 65 is something that affects a lot of us here, and the latest information is worth paying attention to. I'll share what I know and hopefully others can fill in the gaps.

Key points as I understand them:

• This has been evolving over the past few months
• There are different perspectives on how to approach it
• The practical implications depend on your specific situation

What are you all hearing from your providers about this? Anyone have direct experience to share?

To answer the question about GLP-1 therapy in patients over 65 safety and efficacy data — in my experience this comes down to a few key factors.

I have been dealing with this for about 6 months now, and what I have found is that individual responses really do vary. That said, the general consensus on GLP-1 therapy in patients over seems solid.

What specifically worked for me: starting with a lower dose and titrating slowly. I would suggest GraceAZ_72 try the same approach and reporting back.

LibrarianMeg nailed it. Building on that — GLP-1 therapy in patients over 65 is something I discuss with my dietitian regularly, and their clinical perspective aligns with what LibrarianMeg described.

One thing I would add: discussing this with your provider early helps.

Subscribing to this thread. GLP-1 therapy in patients is exactly what I've been researching. 🙏

Clinical perspective on GLP-1 therapy in patients over 65 :

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.